Identification of (Z)-2,3-Diphenylacrylonitrile as Anti-Cancer Molecule in Persian Gulf Sea Cucumber Holothuria parva
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چکیده
منابع مشابه
Identification of (Z)-2,3-Diphenylacrylonitrile as Anti-Cancer Molecule in Persian Gulf Sea Cucumber Holothuria parva
Hepatocellular carcinoma (HCC), also named cancerous hepatoma, is the most common type of malignant neoplasia of the liver. In this research, we screened the Persian Gulf sea cucumber Holothuria parva (H. parva) methanolic sub-fractions for the possible existence of selective toxicity on liver mitochondria isolated from an animal model of HCC. Next, we purified the most active fraction. Thus th...
متن کاملAntioxidant activity of extracts of two species of Sea Cucumber Holothuria parva and Holothuria leucospilota from the Persian Gulf, Iran
Marine animals are among the most important sources of natural products with biological activities because of their secondary metabolites. Many compounds were extracted, purified, identified and studied for their antioxidant, cytotoxic, anti-inflammatory and antibacterial effects from sea cucumber However, very few investigations are available on Persian Gulf sea cucumbers. The antioxidant act...
متن کاملPopulation structure of sea cucumber Holothuria parva by 16S rRNA mitochondrial in the costs of Bushehrand Halileh from Persian Gulf
Population structure of sea cucumber Holothuria parva in the coasts of Bushehr and Halileh from Persian Gulf was determined by 16S rRNA of mitochondrial genome sequencing in autumn and winter seasons of 2019. In Bushehr and Halileh populations, 2 and 4 haplotypes were identified out of 374 nucleotide sites, respectively, and haplotype 2 was the most abundant in Bushehr population and was observ...
متن کاملSelective Toxicity of Persian Gulf Sea Cucumber (Holothuria parva) and Sponge (Haliclona oculata) Methanolic Extracts on Liver Mitochondria Isolated from an Animal Model of Hepatocellular Carcinoma.
BACKGROUND Natural products isolated from marine environments are well known for their pharmacodynamic potential in diverse disease treatments, such as for cancer or inflammatory conditions. Sea cucumbers are marine animals of the phylum Echinoderm and the class Holothuroidea, with leathery skin and gelatinous bodies. Sponges are important components of Persian Gulf animal communities, and the ...
متن کاملDerivation of extracts from Persian Gulf sea cucumber (Holothuria leucospilota) and assessment of its antifungal effect
Sea cucumber is presented as potential marine source of antimicrobial compounds. The purpose of this study is to evaluate antifungal effects of sea cucumber, Holothuria leucospilota, extracts on Aspergillus niger and Candida albicans. Methanol and chloroform extracts of the body wall, gonad and intestine of sea cucumber, H. leucospilota, collected from Persian Gulf, were evaluated for their ant...
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ژورنال
عنوان ژورنال: Marine Drugs
سال: 2017
ISSN: 1660-3397
DOI: 10.3390/md15100314